RESVERATROL has leaders in the anti-aging, anti – cancer world excited

Its early days however early research is showing that it has a powerful effect on cancer prevention, diabetes and the aging process.

The following videos show how Scientists are really excited about the potential benefits of Resveratrol.

 RESVERATROL! ABC News! @ Yahoo!7 Video

Watch CBS Videos Online

There has been much publicity about the benefits of a glass of red wine due to its Resveratrol content and the well respected Dr Perricone recommends one glass of red wine a day due to Resveratrol. He stated that Resveratrol was a powerful heart healthy, anti cancer, anti aging antioxidant. He warned: Just be sure to keep it to one glass and have your wine with a meal to mitigate the inflammatory aspects of the wine

Contrary to what our Wine Industry may lead us to believe Japanese Knotweed is the highest source of Resveratrol and is used in supplements due to its high resveratrol content. It is also found in peanuts.

It was applied topically to mice with skin cancer and scientists are now recruiting humans for trials. Currently the strongest evidence of anti-cancer action of resveratrol exists for tumors it can come into direct contact with, such as skin and gastrointestinal tract tumors. For other cancers the evidence is uncertain, even if massive doses of resveratrol are used.

Resveratrol given orally to mice had no effect on leukemia and lung cancer.

Resveratrol treatment appeared to prevent the development of mammary tumors in animal models; however, it had no effect on the growth of existing tumors. Paradoxically, treatment of pre-pubertal mice with high doses of resveratrol enhanced formation of tumors. Injected in high doses into mice, resveratrol slowed the growth of neuroblastomas.

An experiment on diabetic rats for 30 days showed that Resveratrol has anti-diabetic properties.

Mice fed resveratrol for fifteen weeks had better treadmill endurance than controls.

In November 2008, researchers reported that dietary supplementation with resveratrol significantly reduced plaque formation in animal brains, a component of Alzheimer and other Neurodegenerative diseases. In mice, oral resveratrol produced large reductions in brain plaque in the hypothalamus (-90%), striatum (-89%), and medial cortex (-48%) sections of the brain. In humans it is theorized that oral doses of resveratrol may reduce beta amyloid plaque associated with aging changes in the brain. Researchers theorize that one mechanism for plaque eradication is the ability of resveratrol to chelate (remove) copper.

Dosage:

The Therapeutic Goods Association has approved 100mg three times daily (300mg) daily.

However when comparing the rates used in research on mice and compensating for the fact that humans have slower metabolic rates than mice the equivalent human dose would equate to roughly 4571 mg/day. There is no published evidence anywhere in the scientific literature of any clinical trial for efficacy in humans. There is limited human safety data. Long-term safety has not been evaluated in humans.

Charts and further information on Wikipedia

We would love to hear feedback (good or bad) from those of you that are taking Resveratrol.

Warning: There are companies on the internet that are promoting a free introduction to Resveratrol. Please beware of these companies as you may end up with your credit card being debited indefinitely and find it really hard to stop. Ouch!!

Ref: Wikipedia. TGA.Dr Perricone.